HOUSTON (AP) _ Cam Newton threw two touchdown passes, DeAngelo Williams ran for a score and the Carolina Panthers ended Houston's seven-game winning streak with a 28-13 win over the Texans on Sunday.
 
Newton completed 13 of 23 passes for 149 yards, outplaying opposing rookie quarterback T.J. Yates. The Panthers (5-9) built a 21-0 halftime lead, then ended Houston's second-half rally when linebacker James Anderson intercepted Yates in the end zone midway through the fourth quarter.
 
The Texans (10-4) are playing for home-field advantage in the playoffs after clinching the AFC South last weekend.
 
But their top-ranked defense looked vulnerable without coordinator Wade Phillips, who's on medical leave after undergoing kidney and gall bladder surgery this week. Linebackers coach Reggie Herring made the defensive calls on Sunday.